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Science in the Agentic Era: Structured Experimentation With Ado

Alessandro Pomponio

AI SecurityThe Linux Foundation26 minIntermediateOpen on YouTube ↗

Outlines science in the Agentic Era: Structured Experimentation With Ado and evaluates key implications for security practitioners.

Summary

Coding agents

Alessandra Pomp defines coding agents as LLMs with harnesses for tool use, state, and iterative explore–plan–execute–verify loops—mirroring DevOps and the scientific method.

Science parallel

Research follows the same cycle: question/explore, hypothesis/plan, experiment/execute, analysis/verify—suggesting agents can support rigorous science, not only software delivery.

ADO introduction

ADO (Accelerated Discovery Orchestrator) extends coding agents for science via Pydantic schemas, provenance tracking, structured result stores, plugins, Ray-backed scalable execution, and a CLI usable by humans and agents.

Workflow

Agents retrieve plans and configurations, define discovery spaces, run experiment campaigns, store/query results over time, and verify outcomes through schemas, logs, and sampling trajectories for troubleshooting.

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